Project Overview
Investigating potential correlations between head impacts and changes in the gut microbiome
Department(s)
Biology
Abstract
The gut microbiota include all of the bacteria, fungi, and other microorganisms found in the digestive system, and the gut microbiome is composed of all of the genes present in those organisms. The gut microbiome contributes to the functioning of numerous bodily systems, including the nervous system. In this study, we are examining whether changes in the composition of the gut microbiome correlate with head impacts in collegiate student-athletes. Using data collected from helmet-mounted impact sensors and DNA extracted from participant fecal samples for microbiome sequencing, we will use computational techniques to examine fluctuations in microbiome composition and the relationship between the timing of these fluctuations and subconcussive head impacts. The results of these analyses will inform the development of further studies examining connections between brain health and the gut microbiome.
Student Qualifications
Required:
Completion of at least Biol 182 or equivalent.
Some coursework with statistics and/or computational methods.
Preferred:
Experience collecting and analyzing helmet impact sensor data.
Experience with DNA extraction from biological samples.
Ability to use bioinformatics to analyze large-scale DNA sequence data.
Number of Student Researchers
One students
Project Length
10 weeks