Project Overview

Using an expanded genetic code to study selenoprotein function

Faculty Sponsor

Jenny Peeler (jpeeler@colgate.edu)

Department(s)

Chemistry

Abstract

This project utilizes chemical tools in order to study biological systems. We can engineer human cells to build proteins using an expanded set of amino acids, beyond those that are naturally available to the cells. We specifically use this approach (which is called genetic code expansion) to produce human proteins that are challenging or impossible to produce with traditional techniques. Once we have expressed these proteins, we can then study how they function and what role they play in human biology. Specifically, we will be studying human selenoproteins, which are currently poorly understood, but are suspected to play a role in redox regulation within a cell.
 

Student Qualifications

Chem 102 or Chem 111

Number of Student Researchers

2 students

Project Length

8-10 weeks


Applications open on 01/03/2022 and close on 02/04/2022


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If you have questions, please contact Karyn Belanger (kgbelanger@colgate.edu).